Wang et al(Zhao-Yi et al. 2020) from Hunan University of Chinese Medicine extracted and analyzed the wind-dispelling herbs prescribed by Li Dong-Yuan (李东垣) and many doctors of his school i.e. the Earth Supplementing School (补土派). Data mining showed that there were 23 wind-dispelling medications that were prescribed with a frequency of ≥ 60. The mainly used drugs were Saposhnikoviae Radix (Fang Feng, 防风), Bupleuri Radix (Chai Hu, 柴胡), Cimicifugae Rhizoma (Sheng Ma, 升麻), Notopterygii Rhizoma Et Radix (Qiang Huo, 羌活), Puerariae Lobatae Radix (Ge Gen, 葛根), Chuanxiong Rhizoma (Chuan Xiong, 川芎), and Ephedrae Herba (Ma Huang, 麻黄).
In addition, they analyzed the association rules wind-dispelling herbs and obtained 23 one-to-one drug association rules and 11 multiple-to-one drug association rules. The core drug network analysis data visualization showed core drugs used in the treatment of external wind assailing the exterior (wind-cold, wind-heat, wind-dampness, etc.), wind-stroke, and tonifying middle and replenishing Qi. Factor analysis was performed on the drugs used by LI Dong-Yuan, and finally 4 groups of wind medicine combinations were obtained.
- Zhao-Yi, W.A.N.G., H.U.A.N.G. Zheng-De, Y.A.N.G. Ping, R.E.N. Ting, and L.I. Xin-Hui. 2020. “Regularity of Wind-Dispelling Medication Prescribed by LI Dong-Yuan: A Data Mining Technology-Based Study.” Digital Chinese Medicine, March, 20–33. https://doi.org/10.1016/j.dcmed.2020.03.003.