A research team from Women’s Hospital, Zhejiang University School of Medicine, China released their latest study on the effects of BSTJF (补肾填精方 Bu-Shen-Tian-Jing Formula) on the outcomes of IVF in Chinese patients with PCOS and the potential underlying mechanism. The study involved 111 patients with PCOS who had undergone IVF. Fifty-four patients received a three-month BSTJF herbal medicine therapy before controlled ovarian hyperstimulation, while the other 57 patients didn’t. BSTJF helped patients with PCOS to get more retrieved oocytes (P<0.05) and fertilized oocytes (P<0.05). The clinical cumulative pregnancy rate, live birth rate, and term delivery rate were significantly higher in the same stimulated cycle of the PCOS patients with BSTJF treatment (P<0.05). Therefore the team concluded that BSTJF significantly could improve the outcomes of IVF in Chinese patients with PCOS through decreasing Anti-Müllerian hormone (AMH) levels in follicular fluids.

Basic components of BSTJF to treat PCOS

Chinese Pinyin nameEnglish namePart usedProcessDried herbal daily dosage (g)
Xian Ling PiShort-horned Epimedium HerbLeafDry in the sun or in the shade9
Rou Cong RongDesertliving Cistanche HerbRhizomeDry in the sun9
Bai ZhuLargehead Atractylodes RhRhizomeDry in the sun20
Nv Zhen ZiGlossy Privet FruitMature fruitDry after slightly steamed20
Fu Pen ZiPalmleaf Raspberry FruitFruitDry after slightly steamed10
Tu Si ZiSemen CuscutaeSeedDry in the sun15
Bu Gu ZhiMalaytea Scurfpea FruitFruitDry in the sun15
Huang QiMilkvetch RootRhizomeDry in the sun10
Dan ShenDan-Shen RootRhizomeDry in the sun10
Total prescription weight (g)118
Pan et al. Chinese herbal medicine (Bu-Shen-Tian-Jing Formula) for outcomes of IVF in Chinese patients with polycystic ovary syndrome: a retrospective cohort study.

Pan X, Gu Y, Zhang X et al. Chinese herbal medicine (Bu-Shen-Tian-Jing Formula) for outcomes of IVF in Chinese patients with polycystic ovary syndrome: a retrospective cohort study. Integrative Medicine Research, 2021, 100775

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