Neurologic Complications of Immunotherapy
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Psychology, Neurology, Endocrinology, Immunology, Degeneration
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There is discussion on weather vaccination is a risk factor for MS or not. A research team from Munich reported that vaccination was not a risk factor for MS. On the contrary, they consistently suggested that vaccination be associated with a lower likelihood of being diagnosed with MS within the next 5 years(Hapfelmeier et al. […]
Lee et al 1 compared 135 patients with obstructive sleep apnea (OSA) with 165 healthy controls using fractional anisotropy (FA) analysis to document differences in brain network connectivity as a biomarker of cognitive deficits and brain tissue dysfunction. The study found that differences in the cingulate area and amygdala and lower FA values in the […]
Mechanism Review of Electro-Acupuncture Treating Spinal Cord Injury 来自黑龙江中医药大学的孙忠人教授团队最新发表的综述文章揭示了电针修复脊髓损伤的机制。该团队搜集近年国内外电针治疗脊髓损伤机制研究文献, 从电针促进神经修复、抑制神经细胞凋亡、改善损伤区微环境3个方面综述电针治疗机制.电针促进神经修复主要包括抑制轴突生长抑制因子表达、减少胶质瘢痕的形成、促进神经干细胞分化和神经元的生长等,改善微环境主要包括抑制细胞炎症反应、兴奋性氨基酸毒性和脂质过氧化反应、促进神经营养因子分泌、增加血流量、改善微循环、增强自噬流,最终是促进神经元再生、轴突和髓鞘重塑、抑制神经细胞死亡,各种机制相互关联、互相影响。从分子生物学角度证明电针治疗的多靶点性,为临床治疗脊髓损伤提供研究基础. 参考文献 孙忠人, 田洪昭, 徐思禹, 赵健宏, 栾逸先, 张文钊, 尹洪娜. 电针治疗脊髓损伤机制研究概述. 针灸临床杂志. 2019, 4:84-8.
Liew TM(Liew 2019) from National University of Singapore reported a review based on cohort study. At baseline, 1307 participants (9.7%) had depression and 3582 (26.6%) had subjective cognitive decline (SCD). During follow-up, 1490 (11.1%) developed MCI/dementia. Depression and SCD demonstrated independent risks of MCI/dementia (HR 1.4 and 2.0 respectively). The risk was highest when depression […]
